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Updated: Aug 7, 2026
In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing
Published on: February 6, 2018
[To estimate early postmortem interval by investigating changes of rats' gastrocnemius excitability]
Bin Li1, Hong-Tao Yan, Wei-Jie Chen
1West China School of Basic Medicine and Forensic Sciences of Sichuan University, Chengdu 610041, China. lblyzz@163.com
Objective:
To investigate the changes of excitability of rats' gastrocnemius after rats were died from mechanic asphyxia, so as to make an objective evidence for estimating of the early postmortem interval.
Methods:
After rats were sacrificed by mechanic asphyxia, the reaction of rats' gastrocnemius to variable electric stimulation at different period after death were recorded by electricphysiological method.
Results:
Changes in the properties of excitable tissue to electric stimulate in rats' gastrocnemius after mechanic asphyxia seems to be well correlated with the early postmortem interval and appeared a linear relation in certain period.
Conclusion:
The regular changes of excitability in muscle might be a useful means for estimating of early postmortem interval.
