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Updated: Aug 7, 2026
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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
[Newborn emphysema attributed to medical actions (3 case report)]
1Center of Forebsic Science, Zhejiang University, Hangzhou 300016, China.
Fa Yi Xue Za Zhi
|July 21, 2006
Summary
Newborn emphysema, including parenchymatous, interstitial, and bullous types, can arise from interstitial air accumulation. High-pressure oxygen during first-aid is a potential cause.
Area of Science:
- Neonatal respiratory conditions
- Pulmonary pathology
- Pediatric critical care
Background:
- Emphysema in newborns is rare and presents diagnostic challenges.
- Understanding the pathogenesis of neonatal emphysema is crucial for timely intervention.
Observation:
- Three cases of neonatal emphysema encompassing parenchymatous, interstitial, and bullous forms were documented.
- One case demonstrated significant interstitial air accumulation, tracking into the mediastinum and subcutaneous tissues.
Findings:
- Air accumulation in lung septa can lead to widespread dissemination.
- The pathway involves lung interstitium, mediastinum, and extensive subcutaneous emphysema.
- High-pressure oxygen administration during neonatal resuscitation is implicated as a causative factor.
Implications:
- This highlights the importance of careful oxygen delivery techniques in neonates.
- Early recognition and management of neonatal emphysema are critical for patient outcomes.
- Further research into the biomechanics of air leak in neonates is warranted.
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