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[Antioxidation activities of Fructus Broussonetia haematochrome in vitro]
Su-Qiu Pang1, Guo-Quan Wang, Lu-Ping Qin
1College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Objective:
To investigate the antioxidative effects of Fructus Broussonetia Haematochrome.
Methods:
NADH-PMS-NBT system was used to produce supetoxide free radical (O2-*), Fe(2+) -H2O2 system to generate hydroxyl free radical (*OH), H2O2 to stimulate oxidative hemolysis of erythrocytes of mice. MDA production in liver homogenate induced by auto-oxidation was measured by MDA kits method.
Results:
FBH not only scavenged O2-* and *OH produced by the experimental systems directly, but also inhibited H2O2 stimulated oxidative hemolysis of erythrocytes of mice, depressed MDA production in mice liver homogenate by auto-oxidation and hepatic mitochondria expanded induced by Vit C-Fe2+ system.
Conclusion:
FBH possess an antioxidative activity.
