Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fold-speed control in collapsing mixed phospholipid monolayers.

Yi Zhang1, Thomas M Fischer

  • 1Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, USA.

The Journal of Physical Chemistry. B
|July 21, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Size-Specific Transport of Colloidal Particles Using Magnetic Fields.

Physical review letters·2026
Same author

Topological sorting of magnetic colloidal bipeds.

Soft matter·2025
Same author

Topologically cloaked magnetic colloidal transport.

Nature communications·2025
Same author

Magnetic colloidal single particles and dumbbells on a tilted washboard moiré pattern in a precessing external field.

Soft matter·2024
Same author

Topologically controlled synthesis of active colloidal bipeds.

Nature communications·2024
Same author

Simultaneous and independent topological control of identical microparticles in non-periodic energy landscapes.

Nature communications·2023

Researchers studied lipid monolayers, observing fold dynamics during compression. Increasing the softer dipalmitoylphosphatidylcholine (DPPC) component reduced fold speed, aligning with theoretical predictions for stressed systems.

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Biophysics

Background:

  • Lipid monolayers are crucial for understanding biological membranes.
  • Studying monolayer collapse and folding provides insights into material behavior under stress.

Purpose of the Study:

  • To investigate the effect of lipid composition on monolayer fold dynamics.
  • To analyze the kinetics of secondary fold formation and propagation.

Main Methods:

  • Formation of mixed monolayers of dipalmitoylphosphatidylcholine (DPPC) and dipalmitoyl-phosphatidylserine.
  • Compression of monolayers beyond their collapse pressure.
  • Observation using Brewster angle microscopy and measurement of secondary fold velocity with a fast CCD camera.

Related Experiment Videos

Main Results:

  • Primary and secondary folds were observed growing perpendicular to the compression direction.
  • Secondary fold velocity decreased with an increasing mole fraction of DPPC.
  • The observed fracture kinetics matched theoretical models for fold coarsening in stressed 3D systems.

Conclusions:

  • Lipid composition significantly influences the dynamics of monolayer folding.
  • The study validates theoretical models for fold coarsening in complex lipid systems.
  • Findings contribute to understanding mechanical properties and failure mechanisms of lipid membranes.