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Published on: November 19, 2018
Poly(N-acryloylsarcosine methyl ester) protein-resistant surfaces
D O H Teare1, W C E Schofield, R P Garrod
1Department of Chemistry, Science Laboratories, Durham University, Durham DH1 3LE, England, U.K.
Abstract:
A new class of protein-resistant film based on N-substituted glycine derivatives is described. Pulsed plasma deposited poly(N-acryloylsarcosine methyl ester) coatings are shown to be resistant toward the adsorption of fibrinogen and lysozyme. Deposition and UV irradiation of the polymer through a masked grid are found to be effective ways for generating negative and positive image protein arrays, respectively, onto a range of different substrate materials.

