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Updated: Aug 7, 2026

Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes
Published on: March 14, 2021
Spectroscopic study of lysopalmitoylphosphatidylcholine Newton black films
Florent Sandras1, Christine Grauby-Heywang, Jean-Marie Turlet
1Centre de Physique Moléculaire Optique et Hertzienne, UMR 5798 du CNRS, Université Bordeaux 1, 351 cours de la libération, 33405 Talence Cedex, France.
Abstract:
Lysopalmitoylphosphatidylcholine (LPC) black films have been studied by confocal Raman spectroscopy and their spectra analyzed and compared to their counterparts obtained from LPC in the solid state and aqueous solution. It appears that LPC is able to form stable and highly ordered black films, despite the presence of only one hydrophobic chain in this molecule. A complementary infrared study of LPC Gibbs monolayers suggests that the whole LPC polar head is perpendicular to the air/water interface. Such an orientation could explain the high order and the close packing observed in black films.

