Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ion atmosphere around nucleic acid.

Clifford H Taubes1, Udayan Mohanty, Steven Chu

  • 1Department of Mathematics, Harvard University, Cambridge, Massachusetts 02138, USA.

The Journal of Physical Chemistry. B
|July 21, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamics of Radiation Damage Buildup in Ultrathin Hexagonal Boron Nitride Films under Ion Bombardment.

ACS applied materials & interfaces·2026
Same author

Transient ion-mediated interactions regulate subunit rotation in a eukaryotic ribosome.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Association Between the Emergency Heart Failure Mortality Risk Grade (EHMRG30-ST) and Costs of Care.

CJC open·2026
Same author

Epitaxial Electrodeposition of Fe with Controlled In-Plane Variants for a Reversible Metal Anode in an Aqueous Electrolyte.

Nano letters·2026
Same author

Exploring the Feasibility of the Creyos Cognitive Assessment Tool Among Patients With Heart Failure.

Cureus·2025
Same author

Validation of PROMIS anxiety item bank computer adaptive test among patients with heart failure.

Frontiers in cardiovascular medicine·2025
Same journal

Donor-Acceptor Separation Augments Temperature Dependence of Kinetic Isotope Effects in NADH Model Hydride Transfer Reactions: Mimicking Enzyme versus Mutant Dynamics.

The journal of physical chemistry. B·2026
Same journal

Disordered Worm-Like Clusters in a Hexagonal Mesophase Former: Simulation and Thermodynamic Description.

The journal of physical chemistry. B·2026
Same journal

Comparative Biophysical Analysis of Healthy and Inflamed Intestinal Membrane Models Using Langmuir Monolayers.

The journal of physical chemistry. B·2026
Same journal

Phosphoserine Charge State Drives Ion Condensation and Spatial Polyamine Presentation in Multirepeat Silaffin.

The journal of physical chemistry. B·2026
Same journal

pH-Dependent Conformational Transition of the Glutamate-GABA Antiporter GadC Revealed by <sup>19</sup>F NMR.

The journal of physical chemistry. B·2026
Same journal

Hydrogen-Bond Network in Equimolar <i>N</i>-Methylacetamide-Water: Integrated Neutron Scattering, Molecular Dynamics, DFT-NBO-AIM, and Machine Learning Analysis.

The journal of physical chemistry. B·2026
See all related articles

This study provides precise bounds for the polyion-ion preferential interaction coefficient (Gamma), crucial for understanding ion behavior around charged polymers like DNA. The findings offer insights into ion distribution across various salt concentrations.

Area of Science:

  • Physical Chemistry
  • Biophysics
  • Computational Biology

Background:

  • The polyion-ion preferential interaction coefficient (Gamma) quantifies ion Cloud behavior around charged macromolecules.
  • Understanding ion accumulation and exclusion is vital for biological processes involving polyelectrolytes like DNA and RNA.

Purpose of the Study:

  • To establish rigorous upper and lower bounds for Gamma for an idealized infinite cylinder polyion model.
  • To analyze the salt concentration dependence of Gamma in aqueous solutions.
  • To extend these bounds to finite-length polyions.

Main Methods:

  • Theoretical modeling of ion-polyion interactions in aqueous solutions.
  • Derivation of mathematical bounds for the preferential interaction coefficient.

Related Experiment Videos

  • Analysis of salt dependence across low, intermediate, and high concentration regimes.

    • Main Results:

    • Tight upper and lower bounds for Gamma were derived for infinite cylindrical polyions.
    • The study predicts the salt dependence of Gamma, applicable to DNA and RNA models.
    • Methodology is presented to estimate bounds for finite polyions.

    Conclusions:

    • The derived bounds provide a theoretical framework for predicting ion distribution near polyions.
    • This work advances the understanding of electrostatic interactions in biological macromolecules.
    • The findings are relevant for modeling DNA/RNA behavior in solutions with varying salt content.