Related Experiment Video
Updated: Aug 7, 2026
Anchorage of Twisted Testis: A Rat Model of Ischemia-Reperfusion Injury of the Testis
Published on: November 14, 2025
Melatonin and roentgen irradiation of the testis
Mahmoud R Hussein1, Eman E Abu-Dief, Amal T Abou El-Ghait
1Department of Histopathology, Assir Central Hospital (King Khlid University Teaching Hospitals), Assir, Kingdom of Saudi Arabia. mrh17@swissinfo.org
Abstract:
Melatonin is a free-radical scavenger and antioxidant. Roentgen irradiation of testis (animal model formed of albino rats) was associated with destruction and depletion of the germinal epithelial cells. In roentgen-irradiated, melatonin-pretreated animals, these changes were markedly ameliorated. Thus administration of melatonin before irradiation can protect testis from some of the destructive effects of roentgen irradiation.