Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Perinatal mortality in Rh alloimmunized patients.

Luciano Marcondes Machado Nardozza1, Luiz Camano, Antonio Fernandes Moron

  • 1Fetal Medicine Unit, Obstetrics Department, São Paulo Federal University-Paulista Medical School, UNIFESP-EPM, Av. Lopes de Azevedo, 888, CEP 05603-001, São Paulo, Brazil. lunardozza@uol.com.br

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|July 21, 2006
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility of telephone-based telemedicine for gynecologic oncology follow-up in Brazil's public health system: a descriptive pilot study.

Clinics (Sao Paulo, Brazil)·2026
Same author

Galen vein malformation-intrauterine treatment.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same author

In vitro evaluation of a decellularized human fetal skin-derived scaffold repopulated with human amniotic fluid stem cells for potential application in myelomeningocele repair.

Scientific reports·2026
Same author

Family dynamics after diagnosis and surgical treatment of myelomeningocele: using telemedicine as a complementary tool.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2025
Same author

Serology survey of chikungunya virus in high-risk pregnant women and placental tissue findings.

Revista do Instituto de Medicina Tropical de Sao Paulo·2025
Same author

A pilot study on feasibility and hypothesis exploration: reducing on-scene length of stay of the emergency teams via ambulance dispatch teleconsultation for prehospital examination.

Einstein (Sao Paulo, Brazil)·2025

Perinatal mortality in Rh-negative pregnancies remains high, particularly in alloimmunized cases. Management with amniocentesis or middle cerebral artery Doppler studies showed similar perinatal mortality rates.

Area of Science:

  • Perinatology
  • Maternal-Fetal Medicine
  • Immunology

Background:

  • Rh-negative pregnancies pose risks due to potential alloimmunization.
  • Monitoring fetal well-being is crucial in Rh-negative pregnancies.

Purpose of the Study:

  • To compare perinatal mortality in Rh-negative pregnancies using amniocentesis versus middle cerebral artery peak systolic velocity (Doppler).
  • To evaluate perinatal outcomes in alloimmunized Rh-negative pregnancies.

Main Methods:

  • A descriptive observational study of 291 Rh-negative pregnancies from 1995-2004.
  • Comparison of perinatal mortality between 99 alloimmunized and 192 unimmunized patients.
  • Comparison of perinatal mortality between pregnancies managed with amniocentesis (74) and Doppler studies (25).

Related Experiment Videos

Main Results:

  • Perinatal mortality was significantly higher in alloimmunized patients (12.1%) compared to unimmunized controls (1%).
  • No significant difference in perinatal mortality was observed between amniocentesis (13.5%) and Doppler (8.0%) management.
  • Gestational age and birth weight did not significantly differ between the two management groups.

Conclusions:

  • Perinatal mortality in Rh-negative alloimmunized pregnancies remains high.
  • Current management protocols (amniocentesis or Doppler) do not significantly alter perinatal mortality rates.