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A 4-year survey on palivizumab respiratory syncytial virus (RSV)-prophylaxis: how can compliance be improved?

Maria Serenella Pignotti1, Serena Catarzi, Gianpaolo Donzelli

  • 1Neonatal Medicine, Anna Meyer Children's Hospital, University of Florence, Via L. Giordano 13, 50132 Florence, Italy. m.pignotti@meyer.it

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|July 21, 2006
PubMed

Insights

Compliance with palivizumab prophylaxis for respiratory syncytial virus (RSV) infections was 87%. Infants born to foreign-born or non-native speaking parents had lower compliance, highlighting the need for multilingual education.

Area of Science:

  • Pediatrics
  • Preventive Medicine
  • Infectious Diseases

Background:

  • Respiratory syncytial virus (RSV) infections pose a significant health risk to infants.
  • Palivizumab prophylaxis is a key preventive strategy for high-risk infants.
  • Understanding compliance factors is crucial for program effectiveness.

Purpose of the Study:

  • To identify factors influencing palivizumab prophylaxis compliance.
  • To propose strategies for improving adherence to preventive medicine programs.
  • To analyze barriers to prophylaxis in a pediatric cohort.

Main Methods:

  • A survey evaluated compliance in 216 children receiving palivizumab.
  • Data collected included demographics, neonatal variables, and parental attitudes.
  • A four-year study period allowed for comprehensive analysis.

Main Results:

  • Overall compliance with palivizumab prophylaxis reached 87%.
  • Lower birth weight and younger age at program initiation were linked to better compliance.
  • Being foreign-born or a non-native speaker was the strongest predictor of poor compliance.

Conclusions:

  • Compliance with RSV prophylaxis is lower in infants of foreign-born or non-native speaking parents.
  • Targeted, multilingual educational materials are essential to improve palivizumab program adherence.
  • Addressing language and cultural barriers can enhance preventive medicine outcomes.
Abstract

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