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Interventions for intermittent exotropia.
1International Centre for Eye Health, c/o Cochrane Eyes and Vision Group, London School of Hygiene & Tropical Medicine, Keppel Street, London, UK WC1E 7HT. sarahrhatt@gmail.com
The Cochrane Database of Systematic Reviews
|July 21, 2006
Summary
Unilateral surgery appears more effective than bilateral surgery for intermittent exotropia. More research is needed to establish optimal treatment guidelines for this condition.
Area of Science:
- Ophthalmology
- Clinical Trials
- Strabismus Management
Background:
- Clinical management of intermittent exotropia lacks clear guidelines on intervention timing and effectiveness.
- Optimal surgical and non-surgical treatment strategies remain debated in existing literature.
Purpose of the Study:
- To review randomized trials on intermittent exotropia treatments.
- To analyze intervention criteria and the impact of factors like age on outcomes.
Main Methods:
- Comprehensive literature search including CENTRAL, MEDLINE, EMBASE, PubMed, and LILACS.
- Manual searches of key ophthalmology journals and conference proceedings.
- Inclusion of randomized controlled trials (RCTs) for surgical and non-surgical interventions.
Main Results:
- Only one eligible randomized trial was identified.
- The trial indicated unilateral surgery is more effective than bilateral surgery for basic intermittent exotropia.
Conclusions:
- Current evidence is limited, primarily from retrospective reviews.
- Further well-designed clinical trials are essential to strengthen the evidence base for intermittent exotropia management.