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Updated: Aug 7, 2026
Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
Published on: August 11, 2023
[DNA genotyping of oral epithelial cells by laser capture microdissection]
Li-Hua Gu1, Cheng Zhang, Lian-Kang Chen
1Shanghai Institute of Forensic Science, Shanghai, 200083, China.
Objective:
The STR genotypping of trace oral epithelial cells which are microdissected by laser capture microdissection system (LCM) is explored.
Methods:
The oral epithelial cells are microdissected using a low-power infrared laser by VERITAS Microdissection Instrument. STR loci of Profiler Plus are detected by multiplex PCR procesures.
Results:
DNA genotyping of 7-8 oral epithelial cells are succeeded, and DNA genotyping of 3-4 oral epithelial cells are failed.
Conclusion:
It is viable in genotyping of trace oral epithelial cells by Laser Capture Microdissection as a new technology of seperating single cell.
