Bacterial meningitis exposure during an international flight: lessons for communicable pathogens

Lyrad K Riley1

  • 1USAF School of Aerospace Medicine, Brooks City-Base, TX, USA. rileyl@eucom.mil

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Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
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