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[The clinical course of microalbumiuria in 4 burn patients]
Yuko Ando1, Yoshiaki Terao, Kazunori Yamashita
1Department of Anesthesia, Nagasaki Rousai Hospital, Sasebo 857-0134.
Background:
In burn patients, microvascular permeability is increased. It is difficult to decide the time to administer albumin because it may induce pulmonary edema in the re-filling period. One report shows that microalbuminuria is correlated with endothelial injury and systemic microvascular permeability.
Methods:
We measured urinary albumin/creatinine ratio (ACR) in 4 burn patients for 48 hours after injury.
Results:
In all patients, ACR was elevated in the early period after injury. Moreover, ACR in 2 severe burn patients with burn total body area of over 30% was above the normal range.
Conclusions:
The present results show that ACR seems to be correlated with the level of microvascular permeability in 4 burn patients. We conclude that ACR may be a useful indicator to decide the time to administer albumin to a burn patient. However, further investigation is required to decide the threshold value of ACR in a severe burn patient whose ACR are kept above the normal range in the long-term.
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