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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Postoperative endophthalmitis caused by Sphingomonas paucimobilis
Wendy E Adams1, Maged Habib, Andrew Berrington
1Ophthalmology Department, Sunderland Eye Infirmary, Sunderland, United Kingdom. wendy_stoer@yahoo.com
Journal of Cataract and Refractive Surgery
|July 22, 2006
Summary
Sphingomonas paucimobilis caused recurrent endophthalmitis post-phacoemulsification. Complete resolution required vitrectomy, highlighting this organism
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Endophthalmitis is a severe intraocular infection often following ocular surgery.
- Phacoemulsification is a common cataract surgery technique.
Observation:
- A 73-year-old woman developed recurrent acute endophthalmitis after phacoemulsification.
- The causative organism, Sphingomonas paucimobilis, was identified.
- The infection was resistant to initial medical management.
Findings:
- Sphingomonas paucimobilis, previously undescribed in endophthalmitis cases, caused the infection.
- Complete resolution of endophthalmitis was achieved only after vitrectomy.
- A potential interaction between Sphingomonas paucimobilis and a co-infective organism was observed, possibly explaining the unusual clinical course.
Implications:
- This case expands the spectrum of pathogens causing post-operative endophthalmitis.
- Vitrectomy may be crucial for managing severe or recurrent cases caused by resistant organisms.
- Further research is needed to understand the pathogenicity and treatment of Sphingomonas paucimobilis endophthalmitis.
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