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Childhood asthma and indoor allergens in Native Americans in New York
Simona Surdu1, Lupita D Montoya, Alice Tarbell
1Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, SUNY, One University Place, Room 127, Rensselaer NY, 12144-3445, USA. surdu@albany.edu
Insights
Breastfeeding significantly protected Mohawk children against asthma. While indoor allergens like dust mites and cat dander were common, their link to childhood asthma in this population was not statistically significant.
Area of Science:
- Environmental Health
- Epidemiology
- Pediatrics
Background:
- Childhood asthma prevalence and risk factors are critical public health concerns.
- Native American populations may face unique environmental exposures and health disparities.
- Understanding asthma triggers in Indigenous communities is essential for targeted interventions.
Purpose of the Study:
- To investigate the association between childhood asthma and potential risk factors, particularly indoor allergens.
- To assess environmental exposures in the homes of St. Regis Mohawk children.
- To identify modifiable risk factors for asthma in a specific Native American community.
Main Methods:
- A case-control study involving 25 children with asthma and 25 controls from the St. Regis Mohawk tribe (ages 2-14).
- Exposure assessment included personal interviews and measurement of dust mite (Der p 1) and cat allergen (Fel d 1) levels.
- Statistical analysis examined correlations between asthma and environmental factors like allergens, secondhand smoke, and air pollution.
Main Results:
- Breastfeeding showed a significant protective effect, reducing asthma risk by 5.2-fold in children under 14.
- Higher levels of dust mite and cat allergens were found in many homes, exceeding sensitization thresholds.
- No statistically significant association was found between current asthma and exposure to dust mite or cat allergens, though the trend was positive.
Conclusions:
- Indoor allergens and other environmental factors may contribute to asthma development in Mohawk homes.
- Avoidance of identified risk factors could potentially reduce or delay asthma onset in susceptible children.
- Further research is needed to confirm specific triggers and develop culturally appropriate prevention strategies.
Background:
The objective of this study was to assess the correlation between childhood asthma and potential risk factors, especially exposure to indoor allergens, in a Native American population.
Methods:
A case-control study of St. Regis Mohawk tribe children ages 2-14 years, 25 diagnosed with asthma and 25 controls was conducted. Exposure was assessed based on a personal interview and measurement of mite and cat allergens (Der p 1, Fel d 1) in indoor dust.
Results:
A non-significant increased risk of childhood asthma was associated with self-reported family history of asthma, childhood environmental tobacco smoke exposure, and air pollution. There was a significant protective effect of breastfeeding against current asthma in children less than 14 years (5.2 fold lower risk). About 80% of dust mite and 15% of cat allergen samples were above the threshold values for sensitization of 2 and 1 mug/g, respectively. The association between current asthma and exposure to dust mite and cat allergens was positive but not statistically significant.
Conclusion:
This research identified several potential indoor and outdoor risk factors for asthma in Mohawks homes, of which avoidance may reduce or delay the development of asthma in susceptible individuals.
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Asthma-I: Introduction
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Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Allergic Reactions
Asthma-III: Symptoms and Complications
Classification of Asthma

