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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Serum HER2 levels are increased in patients with chronic heart failure

Patrick J Perik1, Elisabeth G E de Vries, Jourik A Gietema

  • 1Department of Cardiology, Thorax Center, University of Groningen and University Medical Center Groningen. P.O. Box 30001, 9700 RB Groningen, The Netherlands.

European Journal of Heart Failure
|July 25, 2006
PubMed
Abstract

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Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
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