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Updated: Aug 7, 2026

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
12:02

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols

Published on: June 6, 2017

Cell cycle: sustained ERK signalling represses the inhibitors

Andrew D Sharrocks1

  • 1Faculty of Life Sciences, University of Manchester, UK. a.d.sharrocks@man.ac.uk

Current Biology : CB
|July 25, 2006
PubMed
Summary

Cell proliferation depends on ERK pathway signaling duration. Sustained ERK activation leads to cell cycle re-entry by downregulating anti-proliferative genes.

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