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Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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Regulatory T cells in cancer

Marc Beyer1, Joachim L Schultze

  • 1Molecular Tumor Biology and Tumor Immunology Clinic I for Internal Medicine, University of Cologne, Joseph-Stelzmann Str 9/Haus 16, 50931 Cologne, Germany.

Blood
|July 25, 2006
PubMed
Summary

Elevated regulatory T cells (T(reg) cells) are found in many cancers. This review focuses on understanding the mechanisms behind increased T(reg) cells in human malignancies, particularly CD4(+)CD25(high)FOXP3(+) T(reg) cells.

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