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Isolated and syndromic syngnathism: management, implications, and genetics
Jillian K Tomlinson1, Nguyen Thanh Liem, Ravi Savarirayan
1Royal Children's Hospital Melbourne, Australia. jilliantomlinson@hotmail.com
Annals of Plastic Surgery
|July 25, 2006
Summary
Congenital interalveolar synechiae can occur with Van der Woude syndrome and cleft palate, or as an isolated finding. Early detection is key for managing this condition with an excellent prognosis.
Area of Science:
- Oral and Maxillofacial Surgery
- Pediatric Dentistry
- Clinical Genetics
Background:
- Congenital interalveolar synechiae are rare fibrous bands connecting the alveolar ridges.
- These anomalies can present as isolated findings or be associated with genetic syndromes.
Observation:
- Case 1: Interalveolar synechiae associated with Van der Woude syndrome and cleft palate.
- Case 2: Isolated interalveolar synechiae with no syndromic association or family history.
Findings:
- Review of literature on interalveolar synechiae management, genetics, and implications.
- Congenital interalveolar synechiae generally have an excellent prognosis.
Implications:
- Requires thorough examination for associated abnormalities and syndromes.
- Early diagnosis and management are crucial for optimal outcomes.
- Understanding the genetic basis aids in genetic counseling.
