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Flavonoids from Echinops echinatus.

S Singh¹, R K Upadhyay, M B Pandey

¹Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India.

Journal of Asian Natural Products Research

|July 26, 2006

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Researchers isolated a novel isoflavone glycoside, echinoside, and other flavonoids from Echinops echinatus. This study marks the first documentation of these specific compounds in the plant species.

Area of Science:

Phytochemistry
Natural Product Chemistry
Plant Sciences

Background:

Echinops echinatus is a plant species with potential medicinal properties.
Flavonoids are a class of plant secondary metabolites known for their diverse biological activities.

Purpose of the Study:

To isolate and characterize chemical constituents from the whole plant of Echinops echinatus.
To identify novel compounds and report the occurrence of known flavonoids in this species.

Main Methods:

Phytochemical investigation involving isolation techniques.
Structure elucidation using chemical and spectral data (e.g., NMR, Mass Spectrometry).

Main Results:

A new isoflavone glycoside, named echinoside (7), was isolated.

Related Experiment Videos

Six known compounds were identified: 7-hydroxyisoflavone, kaempferol-4'-methylether, kaempferol-7-methylether, myrecetin-3-O-alpha-L-rhamnoside, kaempferol, and kaempferol-3-O-alpha-L-rhamnoside.

The structure of echinoside was confirmed through comprehensive analysis.

Conclusions:

The study successfully isolated and identified several flavonoids from Echinops echinatus.
This research provides the first report on the presence of these specific flavonoids in E. echinatus, contributing to the phytochemical knowledge of the species.