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Updated: Aug 7, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Minimally invasive endoscopic resection of sinonasal malignancies and skull base surgery
1Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua and Chang Jung Christian University, Tainan, Taiwan. 53780@cch.org.tw
Conclusions:
Sinonasal malignancies without far lateral extension, intracranial invasion or orbital infiltration can be safely excised and reconstructed endoscopically with a satisfactory outcome.
Objectives:
To evaluate the safety and efficacy of strictly endoscopic resection of malignant sinonasal neoplasms.
Patients And Methods:
Seven patients with sinonasal malignancies had received a minimally invasive endoscopic resection. Among them, two cases invaded the skull base. All patients were operated with curative intent.
Results:
All the tumors were removed successfully by strictly endoscopic surgery. Two patients who had invasion of the skull base (28.6%) accepted postoperative radiotherapy. No complications associated with the operation occurred. The patients were followed up for 15-57 months (average 36.4 months). No local recurrence was noted in this series to date. The disease-free survival rate was 100% at a mean follow-up duration of 36.4 months.
