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[Pregnancy and chronic inflammatory bowel diseases]
1Klinik und Poliklinik für Innere Medizin, Martin-Luther-Universität Halle-Wittenberg.
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|November 1, 1991
Summary
Ulcerative colitis and Crohn's disease can affect fertility and pregnancy outcomes. While conception is possible, Crohn's disease is linked to higher infertility rates, and certain medications/disease activity may impact birth weight.
Area of Science:
- Gastroenterology and Obstetrics/Gynecology
- Reproductive Medicine
- Perinatology
Context:
- Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic conditions impacting women's reproductive health.
- Understanding the effects of IBD on fertility and pregnancy is crucial for effective patient management and counseling.
- This study examines 107 women with UC or CD to assess pregnancy and fertility outcomes.
Purpose:
- To investigate the influence of ulcerative colitis and Crohn's disease on fertility and pregnancy.
- To evaluate the impact of IBD and its treatments on birth weight and neonatal outcomes.
- To provide guidance on managing IBD during pregnancy.
Summary:
- Pregnancy is feasible in women with inactive or mild Crohn's disease.
- While conception ability is not generally restricted by ulcerative colitis, Crohn's disease is associated with increased infertility rates.
- Low birth weight was observed with prednisolone use and active ulcerative colitis during pregnancy. Treatment with azulfidine and corticosteroids did not affect child development. Prophylactic therapy is recommended for ulcerative colitis.
Impact:
- Highlights the need for careful management of IBD during pregnancy, especially during acute attacks.
- Informs clinical decisions regarding conception, pregnancy management, and therapeutic interventions for women with IBD.
- Emphasizes the importance of individualized treatment plans to optimize outcomes for both mother and child.