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Thermospray liquid chromatography/mass spectrometry of polar beta-blocking drugs: preliminary results
M S Leloux1, W M Niessen, R A van der Hoeven
1Netherlands Institute for Drugs and Doping Research, State University of Utrecht.
Biological Mass Spectrometry
|October 1, 1991
Abstract:
The use of thermospray liquid chromatography for the screening of polar beta-blocking drugs is evaluated. The influence of instrumental parameters on the fragmentation pattern of labetalol, acebutolol, diacetolol, sotalol and atenolol is described. A short biomedical application is presented.