Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy
Resat Dabak1, Oya Uygur-Bayramicli, Cengiz Gemici
1Department of Family Medicine, Kartal State Hospital, Kartal, Istanbul, Turkey.
Aim:
To evaluate late effects of chemoradiation on gastrointestinal mucosa with an endoscopic scoring system and compare it to a clinical scoring system.
Methods:
Twenty-four patients going to receive chemoradiation after gastric surgery underwent endoscopy four wk after surgery and one year after the chemoradiation finished. Upper gastrointestinal findings were recorded according to a system proposed by World Organisation for Digestive Endoscopy (OMED) and clinical scoring was done with RTOG-EORTC radiation morbidity scoring systems.
Results:
There was no significant endoscopic difference in gastric and intestinal mucosa after chemoradiation (P > 0.05) and there was no association between endoscopic scores and clinical scores. Endoscopic changes were minimal.
Conclusion:
Late effects after chemoradiation in operated patients with gastric cancers can be evaluated with an endoscopic scoring system objectively and this system is superior to clinical scoring systems.
