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Updated: Aug 6, 2026

An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
Simultaneous multiwavelength spectrophotometric quantitation of active components in analgesic formulations.
G Sala1, S Maspotch, H Iturriaga
1Department of Chemistry, Analytical Chemistry Laboratory, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
Abstract:
This work deals with the UV spectrophotometric quantitation of a mixture of compounds with overlapped spectra. The mixture spectrum is resolved by use of three computational programs based on different algorithms, namely Multicomponent Analysis (commercial software available from Hewlett-Packard), MULTIC (relying on multiple regression analysis) and SIMPLEX. The results obtained for mixtures of acetylsalicylic acid, acetaminophen and caffeine in commercial analgesic formulations, are compared.
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