Related Experiment Video
Updated: Aug 6, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Replacement of microbiological assay by high-performance liquid chromatographic assay for antibiotics
1Division of Antibiotics and Chemistry, National Institute for Biological Standards and Control, Blanche Lane, Potters Bar, Hertfordshire EN6 3QG, UK.
Abstract:
The current position with respect to the expression of biological potency and chemical purity of antibiotics is reviewed. In particular, attention is drawn to the policies adopted in the USA which have been a source of confusion regarding the expression of biological potency. It is suggested that the opportunity provided by the introduction of high-performance liquid chromatography for the assay of antibiotics should be used to seek adoption of a more consistent approach for expressing antibiotic purity.
More Related Videos
09:09High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity
Published on: November 16, 2016
12:03Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
Published on: April 18, 2019
Related Concept Videos
Automated Microbial Diagnostics
Rapid Identification of Pathogens