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Updated: Oct 10, 2025

Raman and IR Spectroelectrochemical Methods as Tools to Analyze Conjugated Organic Compounds
Published on: October 12, 2018
Drug analysis by Raman and micro-Raman spectroscopy
1Laboratoire de Spectroscopie Infrarouge et Raman, Université de Bordeaux I, 351 cours de la Libération, 33405 Talence, France.
Abstract:
The technique of Raman spectroscopy, resonance Raman spectroscopy and micro-Raman spectroscopy is described for application to drug analysis and investigation. Possibilities and limits are mentioned for qualitative and quantitative analyses as well as for studies of structure and interactions. Some principal interaction modes, such as hydrogen bonding, proton transfer, charge transfer and ion-molecule attraction, are shown to explain drug reactivity. Illustrations are given based on several drug families, in particular vitamins, anti-depressants, cardio-active and anticancer drugs.
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