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Identification of betamethasone and a major metabolite in equine urine
1Equine Drug Testing and Toxicology, NYS College of Veterinary Medicine, Cornell University, 925 Warren Drive, Ithaca, NY 14850, USA.
Abstract:
Betamethasone and its major unconjugated metabolite, 6-beta-hydroxybetamethasone, were detected in equine urine by thin-layer chromatography and characterized by micro-liquid chromatography/mass spectrometry (micro-LC/MS). Their structures were confirmed by a combination of infrared spectroscopy and nuclear magnetic resonance spectroscopy.
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