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Serum adiponectin concentration prior to clinical onset of preeclampsia
Nancy Odden1, Tore Henriksen, Ellen Holter
1Department of Gynaecology and Obstetrics, Rikshospitalet-Radiumhospitalet Medical Center, Oslo, Norway. nancy.odden@rikshospitalet.no
Objective:
This study assesses whether the adipokine adiponectin is a useful marker in pregnant women who subsequently develop preeclampsia (PE).
Methods:
A retrospective case-control study was conducted to measure the total serum levels of adiponectin, measured by radioimmunoassay kit, in serum samples stored in serological biobanks.
Results:
Total serum adiponectin concentrations between the groups were not significantly different (p = 0.22). There were no obvious clinical signs of the preeclamptic inflammatory process at the time when samples were drawn.
Conclusion:
Using this design, total adiponectin appeared not be a useful pre-clinical marker of PE.