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Related Experiment Videos

Ascending aortic aneurysm resection: 15 years' experience.

Zile S Meharwal1, Surendra N Khanna, Abhay Choudhary

  • 1Escorts Heart Institute and Research Center, Okhla Road, New Delhi 110025, India. meharwal@hotmail.com

Asian Cardiovascular & Thoracic Annals
|July 27, 2006
PubMed
Summary

Ascending aortic replacement for aneurysm or dissection shows low hospital mortality. Key risk factors for early death include low ejection fraction and contained rupture, with good long-term survival rates.

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Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Disease

Background:

  • Ascending aortic aneurysms and dissections are life-threatening conditions requiring surgical intervention.
  • The Bentall and Cabrol procedures are common surgical techniques for ascending aortic replacement.

Purpose of the Study:

  • To evaluate the outcomes of ascending aortic replacement for aneurysm and dissection.
  • To identify risk factors for early mortality and assess long-term survival after surgery.

Main Methods:

  • A retrospective review of 148 patients who underwent ascending aortic replacement between 1989 and 2004.
  • Analysis of surgical procedures, including Bentall, Cabrol, and separate replacements.
  • Statistical analysis to determine risk factors for mortality and long-term survival rates.

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Main Results:

  • Hospital mortality was 4.05%.
  • Significant risk factors for early mortality on multivariate analysis were left ventricular ejection fraction ≤30% and contained rupture.
  • Five, 10, and 15-year survival rates were 87.2%, 78.0%, and 60.9%, respectively.

Conclusions:

  • Ascending aortic resection for aneurysm or dissection can be performed with acceptable hospital mortality.
  • Low ejection fraction and contained rupture are critical predictors of early mortality.
  • The procedure offers favorable long-term survival outcomes for patients with ascending aortic pathologies.