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[Effect of inflammation on clinical outcomes in dialysis patients]
1Divisione e Cattedra di Nefrologia, Spedali Civili e Università di Brescia, Brescia-Italy. eziomov@libero.it
Abstract:
There is a growing recognition that uremia is a proinflammatory condition. Chronic uremia-associated inflammation contributes to the pathogenesis of atherosclerosis, anemia, and cardiovascular calcification in patients with end stage renal failure. Many clinical and experimental evidences indicate that the higher the inflammatory status, the higher is morbidity, mortality and the incidence of chronic malnutrition. Aim of this review is to address the main clinical and experimental findings of the effect of chronic inflammation on clinical outcome in dialysis patients.
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Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...