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Updated: Aug 6, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Dengue infection: neurological manifestations and cerebrospinal fluid (CSF) analysis
C N Soares1, L C Faria, J M Peralta
1Neurology Service, HUAP/UFF (Hospital Universitário Antônio Pedro/Universidade Federal Fluminense), Niterói, RJ, Brazil. crist_nsoares@yahoo.com.br
Abstract:
Neurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barré syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system.
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