Fourth ventricle rosette-forming glioneuronal tumor. Case report
Mahlon Johnson1, John Pace, Judy F Burroughs
1Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA. Mahlon_Johnson@URMC.Rochester.edu
Journal of Neurosurgery
|July 29, 2006
Summary
A rare rosette-forming glioneuronal tumor was identified in the fourth ventricle of a young woman. Further study is needed to understand this newly described brain tumor and its management.
Area of Science:
- Neuro-oncology
- Neuropathology
Background:
- Rosette-forming glioneuronal tumors are rare brain neoplasms.
- The fourth ventricle is a critical anatomical location for brain tumors.
Observation:
- A 29-year-old woman presented with a year of dizziness and a month of headaches.
- Cranial CT revealed a circumscribed mass in the inferior cerebellum and fourth ventricle floor.
Findings:
- Histological analysis showed a piloid glial component with Rosenthal fibers and telangiectatic vessels.
- The tumor exhibited complete or incomplete neurocytic rosettes, characteristic of RGNTs.
Implications:
- Distinguishing this RGNT from pilocytic astrocytomas and other gliomas is critical.
- Further research and long-term follow-up are needed to define optimal management strategies for this entity.
