Nuclear characteristics of malignant lymphoma in the brain

In addition to chromatin and nucleoli, various classes of structures were often seen in nuclei of malignant lymphoma, when compared with other brain tumours. Interchromatin, perichromatin, and atypical dense granules could be ribonucleoprotein in nature on basis of their behaviours in enzymatic extraction and EDTA stain. The perichromatin fibrils became visible at the border of the condensed chromatin only after EDTA stain and might contain substrate for HnRNA. Nuclear bodies and intranuclear fibrillar rodlets also were evident.