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Updated: Aug 6, 2026

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
Popliteal-to-distal artery bypass for diabetic limb salvage
A E Brannigan1, K Ahmad, M Tubassum
1Dept of Vascular Surgery, MidWestern Regional Hospital, Limerick.
Background:
Poor long-term survival and significant co-morbidity among diabetic patients with limb ischaemia makes the shortest, simplest revascularisation procedure desirable.
Aim:
Evaluate limb salvage, primary graft patency and peri-operative morbidity rates in diabetic patients undergoing popliteal-to-distal artery bypass for limb salvage.
Methods:
Patients undergoing popliteal-to-distal artery bypass for critical limb ischaemia over a seven-year period were retrospectively identified. Patients operative and follow-up data were entered into a database and limb salvage and patient survival determined using Kaplan Meier survival analysis.
Results:
During the study period 21 popliteal-to-distal artery bypasses were performed on 19 diabetic patients. Mortality rate after one year was 11%. Primary graft patency rates among surviving patients was 81%, 67% and 48% at 1, 2 and 6 years respectively. Amputation was required in three patients.
Conclusion:
Popliteal-to-distal artery bypass produces favourable results in high-risk diabetic patients with critical limb ischaemia.
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