Related Experiment Video
Updated: Aug 6, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
[Stroboscopic assessment of chronic laryngitis]
J Gamboa1, L Echeverría, B Molina
1Servicio de Otorrinolaringología, Hospital Universitario "Príncipe de Asturias", Alcalá de Henares, Madrid. fgamboam@eresmas.com
Absence of vocal fold mucosal wave during laryngostroboscopy strongly indicates severe dysplasia or cancer. A present mucosal wave does not rule out malignant vocal fold lesions.
Area of Science:
- Laryngology
- Vibratory analysis
- Pathology
Context:
- Laryngostroboscopy visualizes vocal fold vibration during phonation.
- Altered viscoelastic properties of the superficial lamina propria disrupt normal vibration and mucosal wave propagation.
- Chronic laryngitis and glottic cancer can affect vocal fold function.
Purpose:
- To correlate laryngostroboscopy findings with histopathological results in patients with chronic laryngitis and glottic cancer.
- To assess the diagnostic value of mucosal wave analysis in identifying vocal fold pathologies.
Summary:
- A retrospective study analyzed 30 laryngoscopies and 25 corresponding laryngostroboscopies.
- 60% of cases with "absence of mucosal wave" showed severe dysplasia or carcinoma.
- 20% of cases with "limited or present mucosal wave" were diagnosed with carcinoma.
Impact:
- Absence of a mucosal wave significantly increases the likelihood of detecting severe dysplasia or vocal fold carcinoma.
- The presence of a mucosal wave does not exclude the possibility of a malignant vocal fold lesion, underscoring the need for biopsy.
Related Concept Videos
Physical Assessment of the Respiratory Tract IV: Auscultation
Breath Sounds
Breath sounds are categorized into vesicular, bronchovesicular, and bronchial.
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like asthma or COPD,...
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...
Larynx
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...

