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Sodium hyaluronate in trabeculectomy: effect on early complications
Gokhan Gulkilik1, Selim Kocabora, Gunay Engin
1Naima Sokak Canik Yali B1/D2 Yesilkoy, Istanbul, Turkey. g.gulkilik@excite.com
Clinical & Experimental Ophthalmology
|July 29, 2006
Summary
Sodium hyaluronate reduces early complications after trabeculectomy, including hypotony and shallow anterior chambers. However, it does not impact hyphema occurrence or resolution.
Area of Science:
- Ophthalmology
- Surgical Innovation
Background:
- Trabeculectomy is a common glaucoma surgery.
- Early postoperative complications can affect visual outcomes.
Purpose of the Study:
- To assess the efficacy of sodium hyaluronate in mitigating early complications following trabeculectomy.
Main Methods:
- A prospective study involving 51 glaucoma patients undergoing trabeculectomy.
- Patients were randomized into two groups: one receiving sodium hyaluronate injection post-suturing, the other receiving balanced salt solution.
- Evaluated visual acuity, intraocular pressure, and early complications.
Main Results:
- Sodium hyaluronate significantly reduced hypotony (8.3% vs. 40.7%), anterior chamber shallowing (8.3% vs. 37%), and choroidal detachment (0% vs. 33.3%).
- No significant difference was observed in the incidence or clearance of hyphema between groups.
- Postoperative intraocular pressure was significantly lower on day one in the sodium hyaluronate group.
Conclusions:
- Sodium hyaluronate is effective in decreasing early postoperative complications such as hypotony, shallow anterior chamber, and choroidal detachment after trabeculectomy.
- It does not influence the occurrence or resolution of hyphema.
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