Related Experiment Video
Updated: Aug 6, 2026

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
Published on: June 3, 2018
Application of genetic approaches to ocular disease
Mark S Ruttum1, Linda M Reis, Elena V Semina
1Medical College of Wisconsin, 925 North 87th Street, Milwaukee, WI 53226, USA. mruttum@mcw.edu
Abstract:
The human eye is a complex organ whose development requires extraordinary coordination of developmental processes. Multiple genes responsible for the proper development and maintenance of the vertebrate eye have been identified and shown to be involved in a variety of debilitating ocular conditions. Genetic diseases involving the eye represent a leading cause of blindness in children and adults. This article summarizes current genetic approaches and their application to studies of ocular disease.
Related Concept Videos
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Pharmacogenomics: Identification of New Drug Targets
Genetic Lingo
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...

