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Perioperative fluid therapy in children: a survey of current prescribing practice
1Department of Anaesthesia, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK.
Insights
Many anaesthetists prescribe hypotonic fluids, increasing children's risk of hyponatraemia. Few departments have fluid policies, and national guidance is needed to ensure safe perioperative fluid therapy for pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Pediatric Fluid Management
- Iatrogenic Hyponatremia
Background:
- Perioperative fluid therapy in children can lead to iatrogenic hyponatraemia.
- Concerns exist regarding the use of dextrose 4%/saline 0.18% in pediatric patients.
- Current fluid prescribing practices and awareness of guidelines among anaesthetists are not well-understood.
Purpose of the Study:
- To survey anaesthetists' current fluid prescribing practices during the perioperative period.
- To assess the availability of departmental fluid protocols.
- To determine anaesthetists' awareness of Royal College of Paediatrics and Child Health (RCPCH) concerns.
Main Methods:
- A questionnaire survey was distributed to 477 consultant anaesthetists in two UK training areas.
- Responses from 203 anaesthetists who anaesthetized children were analyzed.
- Data collected included fluid prescription habits, departmental policies, and awareness of RCPCH guidelines.
Main Results:
- 67.7% of departments lacked a local fluid prescription policy, and 58.1% of anaesthetists were unaware of RCPCH concerns.
- Hypotonic dextrose saline solutions were prescribed intraoperatively by 60.1% and postoperatively by 75.2% of anaesthetists.
- Anaesthetists in specialist pediatric hospitals were more likely to prescribe isotonic fluids intraoperatively and restrict fluids postoperatively.
Conclusions:
- The prevalent use of hypotonic dextrose saline solutions may place children at risk of iatrogenic hyponatraemia.
- Departmental protocols for perioperative fluid prescription in children are infrequently implemented.
- There is a need for national guidance on pediatric perioperative fluid management.
Background:
Fluid therapy in children may be associated with iatrogenic hyponatraemia. We surveyed anaesthetists' current fluid prescribing practice during the perioperative period, departmental fluid protocols and awareness of the concerns of the Royal College of Paediatrics and Child Health (RCPCH) about the use of dextrose 4%/saline 0.18% in children.
Methods:
Questionnaire survey of 477 consultant anaesthetists in two training areas in the UK.
Results:
Responses were received from 289 anaesthetists (60.6%)--responses from the 203 consultants that anaesthetized children were analysed. A total of 67.7% did not have a local departmental policy for fluid prescription, and 58.1% were unaware of the concerns of RCPCH. A total of 60.1% of anaesthetists said that they prescribed hypotonic dextrose saline solutions in the intraoperative period and 75.2% did so in the postoperative period. Anaesthetists working in specialist paediatric hospitals were 5.1 times more likely to prescribe isotonic fluids intraoperatively than those working in district hospitals (95% CI 1.48-17.65, P=0.01), but they all prescribed hypotonic dextrose saline solutions postoperatively. The Holliday and Segar formula for maintenance fluid was quoted by 81.8% of anaesthetists; only 5.9% of anaesthetists would restrict fluids in the immediate postoperative period. Anaesthetists working in specialist paediatric hospitals were 13.2 times more likely to restrict fluids postoperatively than those working in district hospitals (95% CI 2.8-61.8, P=0.001).
Conclusions:
The prescription of hypotonic dextrose saline solutions by anaesthetists may be putting children at risk from iatrogenic hyponatraemia. Departmental protocols for perioperative fluid prescription in children are uncommon. We suggest that national guidance is required.
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