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Assembling a global vaccine development pipeline for infectious diseases in the developing world
Irina Serdobova1, Marie-Paule Kieny
1Axensus, Ltd, consultants, Cheltenham, Gloucestershire.
American Journal of Public Health
|July 29, 2006
Summary
Declining private investment in public health tools has spurred nonprofit innovation. This study proposes a framework for efficient vaccine research and development (R&D) investment, identifying key forces driving the global vaccine pipeline.
Area of Science:
- Public Health
- Vaccinology
- Nonprofit Innovation
Background:
- Private investment in public health tools has decreased due to commercial realities.
- This has led to the rise of research-based, nonprofit organizations.
- Understanding these shifts is crucial for advancing global health.
Purpose of the Study:
- To review current vaccine developments.
- To develop a framework for efficient research and development (R&D) investments in vaccines.
- To identify key forces influencing the vaccine R&D pipeline.
Main Methods:
- Literature review of current vaccine developments.
- Analysis of "push" and "pull" forces in vaccine R&D.
- Examination of the global vaccine pipeline and stakeholder impacts.
Main Results:
- Identification of critical "push" and "pull" factors affecting vaccine R&D.
- Analysis of how these forces impact the global vaccine pipeline.
- Understanding the role of various stakeholders in vaccine development.
Conclusions:
- A collaborative approach among R&D stakeholders is essential.
- Establishing a sustainable global R&D pipeline is necessary.
- Optimizing vaccine and immunization technology delivery requires coordinated efforts.