Multiple pulmonary abscesses caused by Legionella pneumophila infection in an infant with croup

Catherine Myers1, Regula Corbelli, Jacques Schrenzel

  • 1Hôpitaux Universitaires de Genève, Department of Pediatrics. catherine.myers@hcuge.ch

Insights

Legionella pneumophila infections are rare in children. Prolonged corticosteroid use for severe croup in an infant led to multiple lung abscesses, highlighting the need for caution with immunosuppression.

Area of Science:

  • Pediatric infectious diseases
  • Pulmonology
  • Immunology

Background:

  • Legionella infections are typically rare in pediatric populations.
  • Severe croup often requires intensive management, including potential immunosuppressive therapies.

Observation:

  • An infant with severe croup received prolonged high-dose corticosteroid treatment.
  • The infant subsequently developed multiple pulmonary abscesses.

Findings:

  • The pulmonary abscesses were diagnosed as Legionella pneumophila pneumonia.
  • Immunosuppression due to corticosteroids was not initially considered, delaying diagnosis.

Implications:

  • This case underscores the importance of considering Legionella in children with respiratory infections, especially those on prolonged corticosteroid therapy.
  • Clinicians should exercise caution when administering high-dose corticosteroids to pediatric patients with respiratory conditions due to increased infection risk.

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
309
Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
38.2K
Multiple Regression01:25

Multiple Regression

Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
4.0K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
991
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.5K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
630