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Updated: Aug 6, 2026
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Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
[Central serous chorioretinopathy--retinal function and morphology: microperimetry and optical coherence tomography]
C Springer1, H E Völcker, K Rohrschneider
1Augenklinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg. Christina.Springer@med.uni-heidelberg.de
Summary
Central serous chorioretinopathy (CSC) patients show significant visual field defects (scotomata) despite minimal visual acuity loss. Fundus perimetry effectively quantifies these functional deficits, correlating well with retinal thickness.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Visual Electrophysiology
Background:
- Central serous chorioretinopathy (CSC) is a condition affecting the retina.
- Understanding its impact on retinal function and structure is crucial.
Purpose of the Study:
- To evaluate and compare retinal function and morphology in CSC patients.
- Utilize fundus perimetry and optical coherence tomography (OCT) for assessment.
Main Methods:
- 14 eyes of 14 CSC patients underwent fundus perimetry (Microperimeter 1 - MP1) and OCT.
- Analyzed average retinal thickness and differential light threshold (visual field).
Main Results:
- Patients exhibited serous retinal detachment with average thickness of 381+/-82 microm.
- Microperimetry showed an average defect of 8.3+/-3.8 dB, correlating with retinal thickness (r=0.73).
- Maximal retinal thickness and mean threshold values correlated (r=-0.58).
Conclusions:
- MP1 effectively quantifies functional deficits in CSC.
- Despite mild visual acuity reduction, extensive scotomata were detected via fundus perimetry.
- Functional defects correlate well with retinal thickness in CSC patients.