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Related Experiment Videos

Electroconvulsive therapy in patients with epilepsy.

Mary E Lunde1, Elliot K Lee, Keith G Rasmussen

  • 1Mayo Clinic Department of Psychiatry, Rochester, MN 55905, USA.

Epilepsy & Behavior : E&B
|August 1, 2006
PubMed
Summary

Electroconvulsive therapy (ECT) can be safely used in most epileptic patients with psychiatric disorders. This study found that ECT is generally effective and may not require antiepileptic drug dose adjustments.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Neurology

Background:

  • Limited data exist on electroconvulsive therapy (ECT) use in epileptic patients with psychiatric conditions.
  • Safe and effective treatment protocols are needed for this patient population.

Purpose of the Study:

  • To describe the experience of using ECT in 43 epileptic patients.
  • To evaluate the safety and efficacy of ECT in this cohort.

Main Methods:

  • Retrospective case series of 43 epileptic patients undergoing ECT.
  • Monitoring for spontaneous seizures and assessing psychiatric symptom reduction.
  • Evaluation of the need for antiepileptic medication adjustments.

Main Results:

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  • Most patients achieved adequate seizures during ECT, even with antiepileptic medications.
  • Moderate to marked psychiatric symptom improvement was observed in most patients.
  • Seven patients experienced possible seizures, but pseudoseizures or nonictal events were likely in several cases.

    • Conclusions:

    • Electroconvulsive therapy is a viable treatment option for epileptic patients with psychiatric disorders.
    • ECT can often be administered without altering antiepileptic drug dosages.
    • Recommendations for safe ECT administration in epileptic patients are provided.