Intraocular pressure change during hemodialysis
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Updated: Aug 6, 2026

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Published on: October 2, 2020
Aya Doshiro1, Yuriko Ban, Lumi Kobayashi
1Department of Ophthalmology, Nantan General Hospital, Kyoto, Japan.
Purpose:
To evaluate intraocular pressure (IOP) change through hemodialysis and examine other factors to affect IOP change in patients treated with hemodialysis.
Design:
Prospective, observational case series.
Methods:
IOP, blood pressure, and plasma colloid osmotic pressure (COP) were measured in 188 eyes of 95 patients receiving hemodialysis in Nantan General Hospital.
Results:
IOP significantly decreased after hemodialysis (P = 0.006). Body weight, systolic and diastolic blood pressure also decreased significantly (P < 0.001). COP significantly increased (P < 0.001). Change in IOP correlated negatively with COP change (OD; r = -0.196, OS; r = -0.339) and positively with change in body weight (OD; r = -0.278, OS; r = -0.357). IOP tended to increase after hemodialysis in patients receiving hemodialysis for more than 12 years.
Conclusions:
IOP decrease during hemodialysis may be due to COP increase. Patients receiving hemodialysis for a long time are more likely to show IOP increase after hemodialysis.
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