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Published on: October 2, 2020
Intraocular pressure change during hemodialysis
Aya Doshiro1, Yuriko Ban, Lumi Kobayashi
1Department of Ophthalmology, Nantan General Hospital, Kyoto, Japan.
Intraocular pressure (IOP) generally decreases after hemodialysis due to increased plasma colloid osmotic pressure (COP). However, long-term hemodialysis patients may experience an IOP increase.
Area of Science:
- Ophthalmology
- Nephrology
- Internal Medicine
Background:
- Hemodialysis is a critical treatment for end-stage renal disease.
- Understanding its systemic effects, including ocular parameters like intraocular pressure (IOP), is essential.
Purpose of the Study:
- To investigate the changes in intraocular pressure (IOP) following hemodialysis.
- To identify factors influencing IOP fluctuations in patients undergoing hemodialysis.
Main Methods:
- A prospective, observational case series involving 95 patients (188 eyes).
- Measurements included intraocular pressure (IOP), blood pressure, and plasma colloid osmotic pressure (COP).
Main Results:
- A significant decrease in IOP was observed post-hemodialysis (P = 0.006).
- Hemodialysis also led to significant reductions in body weight, blood pressure, and a significant increase in COP (P < 0.001).
- IOP changes correlated negatively with COP and positively with body weight changes.
Conclusions:
- The observed decrease in IOP during hemodialysis is likely attributed to an increase in plasma colloid osmotic pressure (COP).
- Patients with over 12 years of hemodialysis treatment showed a tendency towards increased IOP post-procedure.
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