Microtubule cytoskeleton behavior in the initial steps of host cell invasion by Besnoitia besnoiti
Related Experiment Video
Updated: Aug 6, 2026

Live Imaging of Microtubule Dynamics in Glioblastoma Cells Invading the Zebrafish Brain
Published on: July 29, 2022
Y Reis1, H Cortes, L Viseu Melo
1Instituto de Investigação Científica Tropical, CVZ, CIISA, Av. Universidade Técnica, Lisboa 1300-477, Portugal.
Abstract:
Besnoitia besnoiti is a protozoan parasite responsible for bovine besnoitiosis. Indirect immunofluorescence showed that isolated B. besnoiti possesses a set of subpellicular microtubules, radiating from the apical end and extending for more than 2/3 of the cell body. Upon interaction with the host cell, B. besnoiti undergoes dramatic modifications of shape and surface, as revealed by atomic force microscopy, accompanied by a distinct tubulin labeling on the posterior region. In the host cell, the microtubule cytoskeleton shows a re-arrangement around the invading parasite suggesting a filamentous interaction with the parasite cytoskeleton during invasion.
More Related Videos
Related Concept Videos
Intracellular Movement of Viruses and Bacteria
Cancer Cell Migration through Invadopodia
Microtubule Formation
Microtubules in Cell Motility
Microtubules in Cell Motility
Cytoskeletal Coordination in Cell Migration

