Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Asthma exacerbations . 1: epidemiology.

N W Johnston1, M R Sears

  • 1Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, Ontario, Canada L8N 4A6. njohnsto@sympatico.ca

Thorax
|August 1, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The influence of maternal and infant nutrition on cardiometabolic traits: novel findings and future research directions from four Canadian birth cohort studies.

The Proceedings of the Nutrition Society·2019
Same author

Prospective randomised blinded clinical trial assessing effectiveness of three dental plaque control methods in dogs.

The Journal of small animal practice·2018
Same author

Impact of maternal pre-pregnancy overweight on infant overweight at 1 year of age: associations and sex-specific differences.

Pediatric obesity·2018
Same author

Human milk oligosaccharide profiles and food sensitization among infants in the CHILD Study.

Allergy·2018
Same author

Patterns of allergic sensitization and atopic dermatitis from 1 to 3 years: Effects on allergic diseases.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2017
Same author

Adiponectin, leptin and insulin in breast milk: associations with maternal characteristics and infant body composition in the first year of life.

International journal of obesity (2005)·2017
Same journal

Mediastinal amyloidosis mimicking advanced lung cancer.

Thorax·2026
Same journal

Comparative performance of endobronchial ultrasound-guided sampling techniques in patients with mediastinal lesions: a network meta-analysis.

Thorax·2026
Same journal

Vitamin A and D impact on lung function: differential or common effects across the lifespan?

Thorax·2026
Same journal

The impact of vitamins A and D on lung function and regulatory epigenetics in adult and childhood asthma.

Thorax·2026
Same journal

Radiological factors associated with the recurrence of <i>Mycobacterium avium complex</i> pulmonary disease: a multicentre retrospective cohort study.

Thorax·2026
Same journal

Daughter vesicles in primary diaphragmatic hydatid cyst.

Thorax·2026
See all related articles

Asthma exacerbations are often triggered by environmental factors and viral infections, showing seasonal patterns. Proper asthma control and adherence to inhaled corticosteroid treatment significantly reduce exacerbation risks.

Area of Science:

  • Environmental Health
  • Epidemiology
  • Pulmonology

Background:

  • Asthma exacerbations are influenced by various environmental triggers, including atmospheric and indoor factors, as well as allergens and pollutants encountered in daily life.
  • Respiratory viral infections, predominantly rhinovirus, are a major cause of asthma exacerbations, especially in children.
  • Asthma exacerbations exhibit seasonal patterns, mirroring those of respiratory viruses and aeroallergens, with variations observed between children and adults, and across sexes.

Purpose of the Study:

  • To investigate the environmental and individual factors contributing to asthma exacerbations.
  • To analyze the seasonal trends and demographic differences in asthma exacerbations.
  • To identify predictors of asthma exacerbation risk, including treatment adherence and disease control.

Related Experiment Videos

Main Methods:

  • Review of epidemiological data on asthma exacerbations.
  • Analysis of seasonal patterns of exacerbations in relation to viral infections and environmental exposures.
  • Assessment of the impact of inhaled corticosteroid compliance and asthma control on exacerbation likelihood.

Main Results:

  • Asthma exacerbations are linked to environmental factors, viral infections, and allergens, with distinct seasonal cycles.
  • Exacerbation risk varies by age and sex, with boys at higher risk in childhood and women in adulthood.
  • Simultaneous exposure to viral infections, allergens, or pollutants increases exacerbation risk.
  • Inhaled corticosteroid treatment access and adherence are crucial in preventing exacerbations.
  • Effective asthma control is a key predictor for reducing exacerbations, respiratory failure, and healthcare utilization.

Conclusions:

  • Environmental factors, viral infections, and allergens significantly influence asthma exacerbations.
  • Asthma exacerbation patterns show distinct seasonal and demographic variations.
  • Adherence to inhaled corticosteroids and achieving good asthma control are vital for preventing severe exacerbations and improving patient outcomes.