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Unusual lymphoblastic leukemia/lymphoma in Eastern Iran
1Department of Pathology, Ali Asghar Hospital, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. karimim@sums.ac.ir
Indian Journal of Pediatrics
|August 1, 2006
Summary
This case report details a rare presentation of lymphoblastic lymphoma-leukemia (LBLL) in a child, highlighting unusual oral mass development. Successful treatment led to complete remission, demonstrating effective management of this rare leukemia-lymphoma entity.
Area of Science:
- Pediatric Oncology
- Hematology
- Oncopathology
Background:
- Lymphoblastic lymphoma-leukemia (LBLL) typically presents with mediastinal masses, lymphadenopathy, or effusions.
- Typical oral manifestations of LBLL are uncommon, posing diagnostic challenges.
Observation:
- A six-year-old boy presented with significant enlargement of the maxilla, mandible, soft palate, and gingival hypertrophy.
- These oral symptoms caused secondary respiratory and feeding difficulties.
Findings:
- Morphologic and flowcytometric analysis of bone marrow revealed T-cell acute leukemia.
- The condition was diagnosed as lymphoma-leukemia, likely due to disseminated lymphoblastic lymphoma.
Implications:
- This case underscores the importance of considering rare presentations of LBLL, particularly extensive oral involvement.
- Prompt diagnosis and treatment of such cases can lead to favorable outcomes and long-term remission.