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Updated: Aug 2, 2026
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Idiopathic retroperitoneal fibrosis (Ormond's disease)].
T Nelius1, F Reiher, T Lindenmeir
1Klinik für Urologie, Otto-von-Guericke-Universität Magdeburg, Leipziger Strasse 44, D-39120 Magdeburg. thomas.nelius@medizin.uni-magdeburg.de
Aktuelle Urologie
|August 1, 2006
Summary
Idiopathic retroperitoneal fibrosis (RPF) is a rare inflammatory condition causing ureteral obstruction. Steroid therapy alongside urinary diversion can lead to RPF regression, reserving surgery for refractory cases.
Area of Science:
- Nephrology
- Urology
- Inflammatory Diseases
Background:
- Idiopathic retroperitoneal fibrosis (RPF) is a rare inflammatory condition characterized by extensive retroperitoneal fibrosis.
- Progressive fibrosis can compress retroperitoneal structures, leading to ureteral obstruction and potential renal damage.
- The unknown etiology of RPF contributes to a lack of consensus regarding optimal treatment strategies.
Observation:
- A 60-year-old patient presented with flank pain, hydronephrosis, and a retroperitoneal mass.
- CT-guided biopsy confirmed idiopathic retroperitoneal fibrosis.
- The patient underwent endoluminal urinary diversion for hydronephrosis.
Findings:
- Simultaneous administration of steroids resulted in near-complete regression of retroperitoneal fibrosis.
- Urinary diversion is crucial for protecting renal function in RPF cases.
- Steroid therapy demonstrated significant efficacy in managing RPF progression.
Implications:
- Early urinary diversion is paramount for preserving kidney function in RPF.
- Corticosteroid therapy offers a viable conservative treatment option for RPF, potentially inducing complete regression.
- Surgical intervention should be reserved for cases of RPF refractory to medical management.
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