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Updated: Aug 5, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
Published on: July 6, 2012
[Synthesis of galactomannan sulfates]
Abstract:
The experimental conditions for the sulfation of legume galactomannans were found, which allow for the obtainment of polysaccharides with a high degree of substitution. Sulfate esters of four galactomannans of different composition (galactose content, 16.4-47.5%) were synthesized using the SO3-pyridine complex in dimethylformamide as a sulfating agent. The degree of substitution was as high as 1.4-1.8; it did not correlate with the content of galactose in the polysaccharides. It was found that the degree of sulfation depended on the reaction temperature in the range of 19-60 degrees C.
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